Materials Transactions Online

Materials Transactions, Vol.53 No.03 (2012) pp.565-570
© 2012 The Japan Institute of Metals

Bone Loss and Reduced Bone Quality of the Human Femur after Total Hip Arthroplasty under Stress-Shielding Effects by Titanium-Based Implant

Yoshihiro Noyama1, 2, Takuya Miura1, Takuya Ishimoto1, Takahiro Itaya1, Mitsuo Niinomi3 and Takayoshi Nakano1

1Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, Suita 565-0871, Japan
2Department of Research and Development Division, Nakashima Medical Co., Ltd., Okayama 709-0625, Japan
3Department of Biomaterials Science, Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan

The present work was aimed at clarifying the stress-shielding effect caused by hip-joint implantation into a femur by using a human cadaver with a cementless hip implant. In particular, bone quality was assessed from the standpoint of preferential c-axis orientation of biological apatite (BAp). Comparing the implanted side to the non-implanted side, a finite element analysis (FEA) indicated that artificial hip-joint implantation had a significant stress-shielding effect on the femur. The results also showed a marked decrease in the degree of preferential BAp orientation as well as bone loss in the medial-proximal femur. This is the first report showing a reduction in the degree of preferential BAp orientation due to a stress-shielding effect after artificial hip-joint implantation. Since preferential BAp orientation is an important index for determining bone mechanical function, these findings should be taken into account in future artificial hip-joint designs, especially those involving the stem component.

(Received 2011/11/21; Accepted 2011/12/19; Published 2012/02/25)

Keywords: titanium, biomaterial, total hip arthroplasty, stress-shielding effect, biological apatite (BAp), preferential orientation, bone quality, finite element analysis (FEA)

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